| CASE REPORT |
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| Year : 2022 | Volume
: 7
| Issue : 1 | Page : 96-98 |
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Therapeutic Plasma Exchange using Continuous Flow Cell Separator Machine in a Neuromyelitis Optica Patient Outcome and Analysis
Sourav Mukherjee, Sudipta Sekhar Das, Subrata Sen
Department of Transfusion Medicine, Apollo Multispeciality Hospitals Ltd, Kolkata, India
Correspondence Address:
Dr. Sourav Mukherjee
Department of Transfusion Medicine, Apollo Multispeciality Hospitals Ltd, Kolkata
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/gjtm.gjtm_106_21
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Neuromyelitis optica (NMO) is an inflammatory central nervous system syndrome, associated with serum aquaporin-4 immunoglobulin G antibodies. Autoantibodies against aquaporin-4 (AQP4-IgG), the principal water channel on astrocyte foot processes at the blood brain barrier, are pathogenic in NMO. Acute attacks are managed by high-dose intravenous methylprednisolone,if symptoms fail to resolve, plasma exchange is considered. Here , we present a case of NMO spectrum disorder in a 20 year old lady, failed to pharmacotherapy , was managed by plasma exchange using Spectra Optia Cell Separator machine . Detailed plasma exchange protocol, disease progression and outcome was analysed in this study.
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