Global Journal of Transfusion Medicine

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 6  |  Issue : 2  |  Page : 135--140

Adverse reactions to the donation of platelet by apheresis and related factors in a tertiary level care blood center


Vadivel Arunachalam, Rajendra Kulkarni, Abhishekh Basavarajegowda 
 Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

Correspondence Address:
Dr. Abhishekh Basavarajegowda
Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry
India

Background and Objectives: Although blood donation by apheresis is very safe, it is essential to identify the adverse reactions that happen and address the factors related to it so as to improve the donation experience both to the donors and the center accepting donations. This study was designed to assess the frequency of adverse reaction in donors undergoing apheresis for platelet donation and delineate the factors associated with the occurrence of such adverse donor reactions, if any. Methodology: This was an analytical retrospective study on the available data of all the donors who donated single-donor apheretic platelets in our blood center from January 2014 to October 2018. Results: The overall donor reaction rate was 8.3%, with the majority (4.7%) being a local reaction in the form of a hematoma. The other 3.6% were systemic reactions, among which 2.1% were citrate reactions and 1.5% vasovagal reactions (VVRs). The variables associated with a VVR were body weight <75 kg and diastolic blood pressure of <70 mmHg, whereas for citrate-related toxicities, it was the duration of the procedure and the amount of anticoagulant used. 4.7% of them were localized reactions in the form of the hematoma, which were more common in first-time donors. Conclusion: Adverse donor reactions to plateletpheresis are notable (8.3%) but generally mild. Auditing them to look for factors associated helps us review the policies and improve competencies among the staff to improve the safety of donors.


How to cite this article:
Arunachalam V, Kulkarni R, Basavarajegowda A. Adverse reactions to the donation of platelet by apheresis and related factors in a tertiary level care blood center.Glob J Transfus Med 2021;6:135-140


How to cite this URL:
Arunachalam V, Kulkarni R, Basavarajegowda A. Adverse reactions to the donation of platelet by apheresis and related factors in a tertiary level care blood center. Glob J Transfus Med [serial online] 2021 [cited 2022 Jan 25 ];6:135-140
Available from: https://www.gjtmonline.com/article.asp?issn=2468-8398;year=2021;volume=6;issue=2;spage=135;epage=140;aulast=Arunachalam;type=0