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  Indian J Med Microbiol
 

Figure 1: Molecular bases of DBS-0 allele with hybrid RHD-RHCE/D-RHD. The black boxes represent wild-type RHD exons 1 through 10. The white box represents the RHCE within exon 5. The presence of RHCE within RHD gene in part of exon 5 area causes (F223V), (A226P), (E233Q), and (V238M) amino acid substitutions. A226P substitution (marked red) is responsible for the amplification of RhE allele

Figure 1: Molecular bases of <i>DBS-0</i> allele with hybrid <i>RHD-RHCE/D-RHD</i>. The black boxes represent wild-type <i>RHD</i> exons 1 through 10. The white box represents the <i>RHCE</i> within exon 5. The presence of <i>RHCE</i> within <i>RHD</i> gene in part of exon 5 area causes (F223V), (A226P), (E233Q), and (V238M) amino acid substitutions. A226P substitution (marked red) is responsible for the amplification of RhE allele